Removing the association won’t break anything for those that don’t have the project.
For the person who has the project, the “Find in Dictionary” and “Find related words” menu options will no longer be available. If they were doing interlinear work, some of the glossing choices they have made will not be found.
Also, if they are accessing the Scripture text in FLEx, that access will no longer work.
John+Wickberg
Paratext Support